Carregant...

Chemical Modification of CRISPR gRNAs Eliminate type I Interferon Responses in Human Peripheral Blood Mononuclear Cells

OBJECTIVES: CRISPR/Cas9 is currently the primary tool used for genome editing in mammalian cells. To cleave and alter genomic DNA, both the Cas9 nuclease and a guide RNA (gRNA) must be present in the nucleus. One preferred method of introducing these reagents is direct transfection of a recombinant...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Cytokine Biol
Autors principals: Schubert, Mollie S., Cedrone, Edward, Neun, Barry, Behlke, Mark A., Dobrovolskaia, Marina A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138052/
https://ncbi.nlm.nih.gov/pubmed/30225466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2576-3881.1000121
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!