Treatment with Trichuris suis soluble products during monocyte-to-macrophage differentiation reduces inflammatory responses through epigenetic remodeling

Helminths have strong immunoregulatory properties that may be exploited in treatment of chronic immune disorders, such as multiple sclerosis and inflammatory bowel disease. Essential players in the pathogenesis of these diseases are proinflammatory macrophages. We present evidence that helminths mod...

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Udgivet i:FASEB J
Main Authors: Hoeksema, Marten A., Laan, Lisa C., Postma, Juliette J., Cummings, Richard D., de Winther, Menno P. J., Dijkstra, Christine D., van Die, Irma, Kooij, Gijs
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137957/
https://ncbi.nlm.nih.gov/pubmed/27095802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600343R
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