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Treatment with Trichuris suis soluble products during monocyte-to-macrophage differentiation reduces inflammatory responses through epigenetic remodeling

Helminths have strong immunoregulatory properties that may be exploited in treatment of chronic immune disorders, such as multiple sclerosis and inflammatory bowel disease. Essential players in the pathogenesis of these diseases are proinflammatory macrophages. We present evidence that helminths mod...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Hoeksema, Marten A., Laan, Lisa C., Postma, Juliette J., Cummings, Richard D., de Winther, Menno P. J., Dijkstra, Christine D., van Die, Irma, Kooij, Gijs
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137957/
https://ncbi.nlm.nih.gov/pubmed/27095802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600343R
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