Treatment with Trichuris suis soluble products during monocyte-to-macrophage differentiation reduces inflammatory responses through epigenetic remodeling

Helminths have strong immunoregulatory properties that may be exploited in treatment of chronic immune disorders, such as multiple sclerosis and inflammatory bowel disease. Essential players in the pathogenesis of these diseases are proinflammatory macrophages. We present evidence that helminths mod...

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Veröffentlicht in:FASEB J
Hauptverfasser: Hoeksema, Marten A., Laan, Lisa C., Postma, Juliette J., Cummings, Richard D., de Winther, Menno P. J., Dijkstra, Christine D., van Die, Irma, Kooij, Gijs
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137957/
https://ncbi.nlm.nih.gov/pubmed/27095802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600343R
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