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Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes

Obesity results from an excessive expansion of white adipose tissue (WAT), which is still poorly understood from an etiologic-mechanistic perspective. Here, we report that Nck1, a Src homology domain-containing adaptor, is upregulated during WAT expansion and in vitro adipogenesis. In agreement, Nck...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Haider, Nida, Dusseault, Julie, Larose, Louise
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137712/
https://ncbi.nlm.nih.gov/pubmed/30240612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.07.010
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