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Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes
Obesity results from an excessive expansion of white adipose tissue (WAT), which is still poorly understood from an etiologic-mechanistic perspective. Here, we report that Nck1, a Src homology domain-containing adaptor, is upregulated during WAT expansion and in vitro adipogenesis. In agreement, Nck...
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| Udgivet i: | iScience |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6137712/ https://ncbi.nlm.nih.gov/pubmed/30240612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.07.010 |
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