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Nck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression
BACKGROUND: Activation of the PI3K/Akt pathway mediates crucial cellular functions regulated by receptor tyrosine kinases, such as cell growth, proliferation, survival and metabolism. Previously, we reported that the whole-body knockout of the Src homology domain-containing adaptor protein Nck1 impr...
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| Vydáno v: | Cell Commun Signal |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4236421/ https://ncbi.nlm.nih.gov/pubmed/25398386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0071-9 |
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