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Activation of the PDGFRα-Nrf2 pathway mediates impaired adipocyte differentiation in bone marrow mesenchymal stem cells lacking Nck1

BACKGROUND: The limited options to treat obesity and its complications result from an incomplete understanding of the underlying molecular mechanisms regulating white adipose tissue development, including adipocyte hypertrophy (increase in size) and hyperplasia (increase in number through adipogenes...

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Bibliografiske detaljer
Udgivet i:Cell Commun Signal
Main Authors: Haider, Nida, Larose, Louise
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023715/
https://ncbi.nlm.nih.gov/pubmed/32059739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0506-4
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