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Mitochondrial reactive oxygen species are required for hypoxia-induced degradation of keratin intermediate filaments

Hypoxia can cause stress and structural changes to the epithelial cytoskeleton. The intermediate filament (IF) network is known to reorganize in response to stress. We examined whether rats exposed to hypoxia had altered keratin IF expression in their alveolar epithelial type II (ATII) cells. There...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Na, Ni, Chandel, Navdeep S., Litvan, Juan, Ridge, Karen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137695/
https://ncbi.nlm.nih.gov/pubmed/19897662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-128967
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