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Nonmonotonic Dose–Response Curves Occur in Dose Ranges That Are Relevant to Regulatory Decision-Making

Non-monotonic dose response curves (NMDRCs) occur in cells, tissues, animals and human populations in response to nutrients, vitamins, pharmacological compounds, hormones and endocrine disrupting chemicals (EDCs). Yet, regulatory agencies have argued that NMDRCs are not common, are not found for adv...

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Detalhes bibliográficos
Publicado no:Dose Response
Main Authors: Hill, Corinne E., Myers, J. P., Vandenberg, Laura N.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137554/
https://ncbi.nlm.nih.gov/pubmed/30228814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1559325818798282
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