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Amyloid precursor protein and endosomal–lysosomal dysfunction in Alzheimer’s disease: inseparable partners in a multifactorial disease
Abnormalities of the endosomal–lysosomal network (ELN) are a signature feature of Alzheimer’s disease (AD). These include the earliest known cytopathology that is specific to AD and that affects endosomes and induces the progressive failure of lysosomes, each of which are directly linked by distinct...
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| I publikationen: | FASEB J |
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| Huvudupphovsman: | |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Federation of American Societies for Experimental Biology
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6137496/ https://ncbi.nlm.nih.gov/pubmed/28663518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700359 |
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