A Comprehensive Mutagenesis Screen of the Adhesion GPCR Latrophilin-1/ADGRL1

Adhesion G-protein-coupled receptors (aGPCRs) play critical roles in diverse cellular processes in neurobiology, development, immunity, and numerous diseases. The lack of molecular understanding of their activation mechanisms, especially with regard to the transmembrane domains, hampers further stud...

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Pubblicato in:iScience
Autori principali: Nazarko, Olha, Kibrom, Amanuel, Winkler, Jana, Leon, Katherine, Stoveken, Hannah, Salzman, Gabriel, Merdas, Katarzyna, Lu, Yue, Narkhede, Pradnya, Tall, Gregory, Prömel, Simone, Araç, Demet
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137404/
https://ncbi.nlm.nih.gov/pubmed/30428326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.04.019
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