A Comprehensive Mutagenesis Screen of the Adhesion GPCR Latrophilin-1/ADGRL1

Adhesion G-protein-coupled receptors (aGPCRs) play critical roles in diverse cellular processes in neurobiology, development, immunity, and numerous diseases. The lack of molecular understanding of their activation mechanisms, especially with regard to the transmembrane domains, hampers further stud...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Nazarko, Olha, Kibrom, Amanuel, Winkler, Jana, Leon, Katherine, Stoveken, Hannah, Salzman, Gabriel, Merdas, Katarzyna, Lu, Yue, Narkhede, Pradnya, Tall, Gregory, Prömel, Simone, Araç, Demet
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137404/
https://ncbi.nlm.nih.gov/pubmed/30428326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.04.019
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