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A Comprehensive Mutagenesis Screen of the Adhesion GPCR Latrophilin-1/ADGRL1

Adhesion G-protein-coupled receptors (aGPCRs) play critical roles in diverse cellular processes in neurobiology, development, immunity, and numerous diseases. The lack of molecular understanding of their activation mechanisms, especially with regard to the transmembrane domains, hampers further stud...

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Bibliografiske detaljer
Udgivet i:iScience
Main Authors: Nazarko, Olha, Kibrom, Amanuel, Winkler, Jana, Leon, Katherine, Stoveken, Hannah, Salzman, Gabriel, Merdas, Katarzyna, Lu, Yue, Narkhede, Pradnya, Tall, Gregory, Prömel, Simone, Araç, Demet
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137404/
https://ncbi.nlm.nih.gov/pubmed/30428326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.04.019
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