SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion

Wntless transports Wnt morphogens to the cell surface and is required for Wnt secretion and morphogenic gradients formation. Recycling of endocytosed Wntless requires the sorting nexin-3 (SNX3)-retromer-dependent endosome-to-Golgi transport pathway. Here we demonstrate the essential role of SNX3-ret...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: McGough, Ian J., de Groot, Reinoud E. A., Jellett, Adam P., Betist, Marco C., Varandas, Katherine C., Danson, Chris M., Heesom, Kate J., Korswagen, Hendrik C., Cullen, Peter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137200/
https://ncbi.nlm.nih.gov/pubmed/30213940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06114-3
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi