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Synthesis of multivalent polymer–aptamer conjugates with enhanced inhibitory potency

PURPOSE: We are interested in designing a modular strategy for creating potent multivalent ligands, which frequently can be used as effective inhibitors of undesired biomolecular interactions. For example, such inhibitors might prevent the self-assembly of bacterial toxins or the attachment of a vir...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Martin, Jacob T, Douaisi, Marc, Arsiwala, Ammar, Arha, Manish, Kane, Ravi S
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136935/
https://ncbi.nlm.nih.gov/pubmed/30237711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S174673
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