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Viral Capsid DNA Aptamer Conjugates as Multivalent Cell Targeting Vehicles

Nucleic acid aptamers offer significant potential as convenient and evolvable targeting groups for drug delivery. To attach them to the surface of a genome-free viral capsid carrier, an efficient oxidative coupling strategy has been developed. The method involves the periodate-mediated reaction of p...

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Detalhes bibliográficos
Main Authors: Tong, Gary J., Hsiao, Sonny C., Carrico, Zachary M., Francis, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737063/
https://ncbi.nlm.nih.gov/pubmed/19603808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja903857f
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