The clinical significance of PD-L1 in advanced gastric cancer is dependent on ARID1A mutations and ATM expression

Whether PD-L1 expression is associated with survival outcomes in gastric cancer (GC) is controversial. The inhibition of the PD-1/PD-L1 pathway is effective against genomically unstable tumors. Hypothesizing that also the clinical significance of PD-L1 might be dependent on the activation of molecul...

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Publicat a:Oncoimmunology
Autors principals: Buglioni, Simonetta, Melucci, Elisa, Sperati, Francesca, Pallocca, Matteo, Terrenato, Irene, De Nicola, Francesca, Goeman, Frauke, Casini, Beatrice, Amoreo, Carla Azzurra, Gallo, Enzo, Diodoro, Maria Grazia, Pescarmona, Edoardo, Vici, Patrizia, Sergi, Domenico, Pizzuti, Laura, Di Lauro, Luigi, Mazzotta, Marco, Barba, Maddalena, Fanciulli, Maurizio, Vitale, Ilio, De Maria, Ruggero, Ciliberto, Gennaro, Maugeri-Saccà, Marcello
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136851/
https://ncbi.nlm.nih.gov/pubmed/30221053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1457602
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