Adoptive immunotherapy with haploidentical natural killer cells and Anti-GD2 monoclonal antibody m3F8 for resistant neuroblastoma: Results of a phase I study

Natural killer (NK) cell-mediated antibody-dependent toxicity is a potent mechanism of action of the anti-GD2 murine monoclonal antibody 3F8 (m3F8). Killer immunoglobulin-like receptor (KIR) and HLA genotypes modulate NK activity and are key prognostic markers in m3F8-treated patients with neuroblas...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Modak, Shakeel, Le Luduec, Jean-Benoit, Cheung, Irene Y., Goldman, Debra A., Ostrovnaya, Irina, Doubrovina, Ekaterina, Basu, Ellen, Kushner, Brian H., Kramer, Kim, Roberts, Stephen S., O'Reilly, Richard J., Cheung, Nai-Kong V., Hsu, Katharine C.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136849/
https://ncbi.nlm.nih.gov/pubmed/30221057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1461305
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