Distinct Roles for Bruton's Tyrosine Kinase in B Cell Immune Synapse Formation

Bruton's tyrosine kinase (Btk) has a key role in the signaling pathways of receptors essential for the B lymphocyte response. Given its implication in B cell-related immunodeficiencies, leukemias/lymphomas and autoimmunity, Btk is studied intensely and is a target for therapy. Here, using prima...

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Publicat a:Front Immunol
Autors principals: Roman-Garcia, Sara, Merino-Cortes, Sara V., Gardeta, Sofia R., de Bruijn, Marjolein J. W., Hendriks, Rudi W., Carrasco, Yolanda R.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136277/
https://ncbi.nlm.nih.gov/pubmed/30237801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02027
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