A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs

Differentiation of human pluripotent stem cells (hPSCs) into striatal medium spiny neurons (MSNs) promises a cell-based therapy for Huntington's disease. However, clinical-grade MSNs remain unavailable. Here, we developed a chemical recipe named XLSBA to generate clinical-grade MSNs from embryo...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Wu, Menghua, Zhang, Da, Bi, Chunying, Mi, Tingwei, Zhu, Wenliang, Xia, Longkuo, Teng, Zhaoqian, Hu, Baoyang, Wu, Yihui
Format: Artigo
Language:Inglês
Published: Elsevier 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135866/
https://ncbi.nlm.nih.gov/pubmed/30174316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.08.005
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