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A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs
Differentiation of human pluripotent stem cells (hPSCs) into striatal medium spiny neurons (MSNs) promises a cell-based therapy for Huntington's disease. However, clinical-grade MSNs remain unavailable. Here, we developed a chemical recipe named XLSBA to generate clinical-grade MSNs from embryo...
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| Pubblicato in: | Stem Cell Reports |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6135866/ https://ncbi.nlm.nih.gov/pubmed/30174316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.08.005 |
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