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Preserving prion strain identity upon replication of prions in vitro using recombinant prion protein

Last decade witnessed an enormous progress in generating authentic infectious prions or PrP(Sc) in vitro using recombinant prion protein (rPrP). Previous work established that rPrP that lacks posttranslational modification is able to support replication of highly infectious PrP(Sc) with assistance o...

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Detaylı Bibliyografya
Yayımlandı:Acta Neuropathol Commun
Asıl Yazarlar: Makarava, Natallia, Savtchenko, Regina, Lasch, Peter, Beekes, Michael, Baskakov, Ilia V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134792/
https://ncbi.nlm.nih.gov/pubmed/30208966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0597-y
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