Preserving prion strain identity upon replication of prions in vitro using recombinant prion protein

Last decade witnessed an enormous progress in generating authentic infectious prions or PrP(Sc) in vitro using recombinant prion protein (rPrP). Previous work established that rPrP that lacks posttranslational modification is able to support replication of highly infectious PrP(Sc) with assistance o...

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Sparad:
Bibliografiska uppgifter
I publikationen:Acta Neuropathol Commun
Huvudupphovsmän: Makarava, Natallia, Savtchenko, Regina, Lasch, Peter, Beekes, Michael, Baskakov, Ilia V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134792/
https://ncbi.nlm.nih.gov/pubmed/30208966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0597-y
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