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Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1

Amyloid diseases represent a growing social and economic burden in the developed world. Understanding the assembly pathway and the inhibition of amyloid formation is key to developing therapies to treat these diseases. The neurodegenerative condition Machado–Joseph disease is characterised by the se...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Mass Spectrom (Chichester)
Hauptverfasser: Knight, Patrick D, Karamanos, Theodoros K, Radford, Sheena E, Ashcroft, Alison E
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134688/
https://ncbi.nlm.nih.gov/pubmed/29334808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1469066717729298
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