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Inhibition of NF-κB in astrocytes is sufficient to delay neurodegeneration induced by proteotoxicity in neurons

BACKGROUND: Most neurodegenerative diseases associated with protein aggregation are hallmarked by activation of astrocytes. However, how astrocytes are activated or which signaling pathways in astrocytes contribute to pathogenesis is not clear. One long-standing question is whether the responses in...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Li, Y. X., Sibon, O. C. M., Dijkers, P. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134576/
https://ncbi.nlm.nih.gov/pubmed/30205834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1278-2
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