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Inhibition of NF-κB in astrocytes is sufficient to delay neurodegeneration induced by proteotoxicity in neurons

BACKGROUND: Most neurodegenerative diseases associated with protein aggregation are hallmarked by activation of astrocytes. However, how astrocytes are activated or which signaling pathways in astrocytes contribute to pathogenesis is not clear. One long-standing question is whether the responses in...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Li, Y. X., Sibon, O. C. M., Dijkers, P. F.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134576/
https://ncbi.nlm.nih.gov/pubmed/30205834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1278-2
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