Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations

Germline coding variants have not been systematically investigated for pancreatic ductal adenocarcinoma (PDAC). Here we report an exome-wide investigation using the Illumina Human Exome Beadchip with 943 PDAC cases and 3908 controls in the Chinese population, followed by two independent replicate sa...

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Publicat a:Nat Commun
Autors principals: Chang, Jiang, Tian, Jianbo, Zhu, Ying, Zhong, Rong, Zhai, Kan, Li, Jiaoyuan, Ke, Juntao, Han, QiangQiang, Lou, Jiao, Chen, Wei, Zhu, Beibei, Shen, Na, Zhang, Yi, Gong, Yajie, Yang, Yang, Zou, Danyi, Peng, Xiating, Zhang, Zhi, Zhang, Xuemei, Huang, Kun, Yang, Ming, Wang, Li, Wu, Chen, Lin, Dongxin, Miao, Xiaoping
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134090/
https://ncbi.nlm.nih.gov/pubmed/30206226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06136-x
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