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A functional variant in GREM1 confers risk for colorectal cancer by disrupting a hsa-miR-185-3p binding site
The transforming growth factor beta (TGF-β) pathway has been implicated in carcinogenesis of intestinal canal. Except for common variants indentified by genome-wide association studies, variants with lower frequency can also explain a part of the disease heritability, especially those in gene regula...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617425/ https://ncbi.nlm.nih.gov/pubmed/28977865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18095 |
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