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BRCA1 missense polymorphisms are associated with poor prognosis of pancreatic cancer patients in a Chinese population

Pancreatic cancer is a highly lethal disease with limited prognostic marker. BRAC1 and BRCA2 are two classic tumor suppressor genes which play an important role in DNA repair. Somatic mutations and germline genetic variants on BRCA1/2 have been found associated with the tumorigenesis of pancreatic c...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Zhu, Ying, Zhai, Kan, Ke, Juntao, Li, Jiaoyuan, Gong, Yajie, Yang, Yang, Tian, Jianbo, Zhang, Yi, Zou, Danyi, Peng, Xiating, Gong, Jing, Zhong, Rong, Huang, Kun, Chang, Jiang, Miao, Xiaoping
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482636/
https://ncbi.nlm.nih.gov/pubmed/28415599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16422
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