Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target

Although annual influenza epidemics affect around 10% of the global population, current treatment options are limited and development of new antivirals is needed. Here, using quantitative phosphoproteomics, we reveal the unique phosphoproteome dynamics that occur in the host cell within minutes of i...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yángüez, Emilio, Hunziker, Annika, Dobay, Maria Pamela, Yildiz, Soner, Schading, Simon, Elshina, Elizaveta, Karakus, Umut, Gehrig, Peter, Grossmann, Jonas, Dijkman, Ronald, Schmolke, Mirco, Stertz, Silke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133941/
https://ncbi.nlm.nih.gov/pubmed/30206219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06119-y
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