Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target

Although annual influenza epidemics affect around 10% of the global population, current treatment options are limited and development of new antivirals is needed. Here, using quantitative phosphoproteomics, we reveal the unique phosphoproteome dynamics that occur in the host cell within minutes of i...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Yángüez, Emilio, Hunziker, Annika, Dobay, Maria Pamela, Yildiz, Soner, Schading, Simon, Elshina, Elizaveta, Karakus, Umut, Gehrig, Peter, Grossmann, Jonas, Dijkman, Ronald, Schmolke, Mirco, Stertz, Silke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133941/
https://ncbi.nlm.nih.gov/pubmed/30206219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06119-y
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