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Cathepsin W Is Required for Escape of Influenza A Virus from Late Endosomes
Human cathepsin W (CtsW) is a cysteine protease, which was identified in a genome-wide RNA interference (RNAi) screen to be required for influenza A virus (IAV) replication. In this study, we show that reducing the levels of expression of CtsW reduces viral titers for different subtypes of IAV, and...
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| Published in: | mBio |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Microbiology
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4462628/ https://ncbi.nlm.nih.gov/pubmed/26060270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00297-15 |
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