Ubiquinol promotes retinal ganglion cell survival and blocks the apoptotic pathway in ischemic retinal degeneration

Coenzyme Q10 (CoQ(10)) protects retinal ganglion cells (RGCs) in experimental retinal ischemia and glaucoma by scavenging reactive oxygen species. We tested whether a diet supplemented with ubiquinol, the reduced form of CoQ(10), promotes RGC survival and blocks the apoptotic pathway in ischemic mou...

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Udgivet i:Biochem Biophys Res Commun
Main Authors: Ju, Won-Kyu, Shim, Myoung Sup, Kim, Keun-Young, Bu, Jung Hyun, Park, Tae Lim, An, Sangphil, Weinreb, Robert N.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133725/
https://ncbi.nlm.nih.gov/pubmed/30107910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.08.016
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