Ubiquinol promotes retinal ganglion cell survival and blocks the apoptotic pathway in ischemic retinal degeneration

Coenzyme Q10 (CoQ(10)) protects retinal ganglion cells (RGCs) in experimental retinal ischemia and glaucoma by scavenging reactive oxygen species. We tested whether a diet supplemented with ubiquinol, the reduced form of CoQ(10), promotes RGC survival and blocks the apoptotic pathway in ischemic mou...

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Gepubliceerd in:Biochem Biophys Res Commun
Hoofdauteurs: Ju, Won-Kyu, Shim, Myoung Sup, Kim, Keun-Young, Bu, Jung Hyun, Park, Tae Lim, An, Sangphil, Weinreb, Robert N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133725/
https://ncbi.nlm.nih.gov/pubmed/30107910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.08.016
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