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Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers

The HypF protein is involved in the maturation and regulation of hydrogenases. The N-terminal domain of HypF (HypF-N) has served as a key model system to study the pathways of protein amyloid formation and the nature of the toxicity of pre-fibrilar protein oligomers. This domain can aggregate into t...

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Dades bibliogràfiques
Publicat a:Biomol NMR Assign
Autors principals: Patel, Jayneil R., Xu, Yingqi, Capitini, Claudia, Chiti, Fabrizio, De Simone, Alfonso
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132818/
https://ncbi.nlm.nih.gov/pubmed/29786756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-018-9822-7
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