PKCι and YAP1 are crucial in promoting pancreatic tumorigenesis

Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignant disease with 5-year survival rate of less than 6%. Activating mutations of Kras (mu-Kras) are often detected in most of PDAC patients. Although it has been known that oncogenic Kras is the driver of pancreatic cancer initiation and develop...

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Опубликовано в: :Oncotarget
Главные авторы: Wang, Peipei, Wei, Dapeng, Zhang, Hongmei, Chen, Jiao, Zhang, Dingding, Ganapathy, Suthakar, Isakson, Pauline, Chen, Changyan, Zhu, Tongbo
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2018
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132349/
https://ncbi.nlm.nih.gov/pubmed/30214681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25127
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