Roles of PKC Isoforms in the Induction of Apoptosis Elicited by Aberrant Ras

Emerging evidence indicates that suppression of protein kinase C (PKC) renders the susceptibility of cells expressing mutated ras to apoptosis. Although the effort has been made, the underlying molecular mechanisms are not fully understood. Here, using shRNAs or PKC inhibitor, we demonstrate that th...

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Bibliographic Details
Main Authors: Zhu, Tongbo, Tsuji, Takanori, Chen, Changyan
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517889/
https://ncbi.nlm.nih.gov/pubmed/19838205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.344
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