Trimetazidine Attenuates Cardiac Dysfunction in Endotoxemia and Sepsis by Promoting Neutrophil Migration

Aims: Cardiac dysfunction can be a fatal complication during severe sepsis. The migration of neutrophils is significantly impaired during severe sepsis. We sought to determine the role of trimetazidine (TMZ) in regulation of neutrophil migration to the heart in a mouse model of sepsis and endotoxemi...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Chen, Jing, Wang, Bei, Lai, Jinsheng, Braunstein, Zachary, He, Mengying, Ruan, Guoran, Yin, Zhongwei, Wang, Jin, Cianflone, Katherine, Ning, Qin, Chen, Chen, Wang, Dao Wen
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131494/
https://ncbi.nlm.nih.gov/pubmed/30233596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02015
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