An oligosaccharyltransferase from Leishmania major increases the N‐glycan occupancy on recombinant glycoproteins produced in Nicotiana benthamiana

N‐glycosylation is critical for recombinant glycoprotein production as it influences the heterogeneity of products and affects their biological function. In most eukaryotes, the oligosaccharyltransferase is the central‐protein complex facilitating the N‐glycosylation of proteins in the lumen of the...

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Veröffentlicht in:Plant Biotechnol J
Hauptverfasser: Castilho, Alexandra, Beihammer, Gernot, Pfeiffer, Christina, Göritzer, Kathrin, Montero‐Morales, Laura, Vavra, Ulrike, Maresch, Daniel, Grünwald‐Gruber, Clemens, Altmann, Friedrich, Steinkellner, Herta, Strasser, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131413/
https://ncbi.nlm.nih.gov/pubmed/29479800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12906
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