Coupling of a specific photoreactive triple-helical peptide to crosslinked collagen films restores binding and activation of DDR2 and VWF

Collagen-based scaffolds may require chemical crosslinking to achieve mechanical properties suitable for tissue engineering. Carbodiimide treatment, often used for this purpose, consumes amino acid side chains required for receptor recognition, thus reducing cell–collagen interaction. Here, we resto...

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發表在:Biomaterials
Main Authors: Malcor, Jean-Daniel, Juskaite, Victoria, Gavriilidou, Despoina, Hunter, Emma J., Davidenko, Natalia, Hamaia, Samir, Sinha, Sanjay, Cameron, Ruth E., Best, Serena M., Leitinger, Birgit, Farndale, Richard W.
格式: Artigo
語言:Inglês
出版: Elsevier Science 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131271/
https://ncbi.nlm.nih.gov/pubmed/30099278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.07.050
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