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Activation mechanisms of the Hippo kinase signaling cascade

First discovered two decades ago through genetic screens in Drosophila, the Hippo pathway has been shown to be conserved in metazoans and controls organ size and tissue homeostasis through regulating the balance between cell proliferation and apoptosis. Dysregulation of the Hippo pathway leads to ab...

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Dettagli Bibliografici
Pubblicato in:Biosci Rep
Autori principali: Bae, Sung Jun, Luo, Xuelian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131212/
https://ncbi.nlm.nih.gov/pubmed/30038061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20171469
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