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Activation mechanisms of the Hippo kinase signaling cascade

First discovered two decades ago through genetic screens in Drosophila, the Hippo pathway has been shown to be conserved in metazoans and controls organ size and tissue homeostasis through regulating the balance between cell proliferation and apoptosis. Dysregulation of the Hippo pathway leads to ab...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Bae, Sung Jun, Luo, Xuelian
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131212/
https://ncbi.nlm.nih.gov/pubmed/30038061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20171469
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