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Rational Design of Thiolase Substrate Specificity for Metabolic Engineering Applications
Metabolic engineering efforts require enzymes that are both highly active and specific towards the synthesis of a desired output product in order to be commercially feasible. The 3-hydroxyacid pathway (3HA), also known as the reverse β-oxidation (r-BOX) or coenzyme-A dependent chain elongation pathw...
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| Veröffentlicht in: | Biotechnol Bioeng |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6131064/ https://ncbi.nlm.nih.gov/pubmed/29877597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26737 |
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