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Oligomerization Alters Binding Affinity Between Amyloid Beta and a Modulator of Peptide Aggregation
The soluble oligomeric form of the amyloid beta (Aβ) peptide is the major causative agent in the molecular pathogenesis of Alzheimer’s disease (AD). We have previously developed a pyrroline-nitroxyl fluorene compound (SLF) that blocks the toxicity of Aβ. Here we introduce the multi-parametric surfac...
में बचाया:
| में प्रकाशित: | J Phys Chem C Nanomater Interfaces |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6130836/ https://ncbi.nlm.nih.gov/pubmed/30214656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcc.7b06164 |
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