Virtual Screening of Chemical Compounds for Discovery of Complement C3 Ligands

[Image: see text] The complement system is our first line of defense against foreign pathogens, but when it is not properly regulated, complement is implicated in the pathology of several autoimmune and inflammatory disorders. Compstatin is a peptidic complement inhibitor that acts by blocking the c...

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Udgivet i:ACS Omega
Main Authors: Mohan, Rohith R., Wilson, Mark, Gorham, Ronald D., Harrison, Reed E. S., Morikis, Vasilios A., Kieslich, Chris A., Orr, Asuka A., Coley, Alexis V., Tamamis, Phanourios, Morikis, Dimitrios
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2018
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130793/
https://ncbi.nlm.nih.gov/pubmed/30221234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00606
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