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Virtual Screening of Chemical Compounds for Discovery of Complement C3 Ligands

[Image: see text] The complement system is our first line of defense against foreign pathogens, but when it is not properly regulated, complement is implicated in the pathology of several autoimmune and inflammatory disorders. Compstatin is a peptidic complement inhibitor that acts by blocking the c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Omega
Prif Awduron: Mohan, Rohith R., Wilson, Mark, Gorham, Ronald D., Harrison, Reed E. S., Morikis, Vasilios A., Kieslich, Chris A., Orr, Asuka A., Coley, Alexis V., Tamamis, Phanourios, Morikis, Dimitrios
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2018
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130793/
https://ncbi.nlm.nih.gov/pubmed/30221234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00606
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