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Virtual Screening of Chemical Compounds for Discovery of Complement C3 Ligands

[Image: see text] The complement system is our first line of defense against foreign pathogens, but when it is not properly regulated, complement is implicated in the pathology of several autoimmune and inflammatory disorders. Compstatin is a peptidic complement inhibitor that acts by blocking the c...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Mohan, Rohith R., Wilson, Mark, Gorham, Ronald D., Harrison, Reed E. S., Morikis, Vasilios A., Kieslich, Chris A., Orr, Asuka A., Coley, Alexis V., Tamamis, Phanourios, Morikis, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130793/
https://ncbi.nlm.nih.gov/pubmed/30221234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00606
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