Loading...
Mutational signature distribution varies with DNA replication timing and strand asymmetry
BACKGROUND: DNA replication plays an important role in mutagenesis, yet little is known about how it interacts with other mutagenic processes. Here, we use somatic mutation signatures—each representing a mutagenic process—derived from 3056 patients spanning 19 cancer types to quantify the strand asy...
Saved in:
| Published in: | Genome Biol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2018
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6130095/ https://ncbi.nlm.nih.gov/pubmed/30201020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1509-y |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|