Engineering of 3-ketosteroid-∆(1)-dehydrogenase based site-directed saturation mutagenesis for efficient biotransformation of steroidal substrates

BACKGROUND: Biosynthesis of steroidal drugs is of great benefit in pharmaceutical manufacturing as the process involves efficient enzymatic catalysis at ambient temperature and atmospheric pressure compared to chemical synthesis. 3-ketosteroid-∆(1)-dehydrogenase from Arthrobacter simplex (KsdD3) cat...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Microb Cell Fact
Autori principali: Mao, Shuhong, Wang, Jian-Wen, Liu, Fufeng, Zhu, Zhangliang, Gao, Dengke, Guo, Qianqian, Xu, Panpan, Ma, Zheng, Hou, Yali, Cheng, Xiaotao, Sun, Dengyue, Lu, Fuping, Qin, Hui-Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130075/
https://ncbi.nlm.nih.gov/pubmed/30200975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-0981-0
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi