Wordt geladen...
Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion
Friedreich’s ataxia (FRDA) is an incurable neurodegenerative disorder caused by reduced expression of the mitochondrial protein frataxin (FXN). The genetic cause of the disease is an expanded GAA repeat within the FXN gene. Agents that increase expression of FXN protein are a potential approach to t...
Bewaard in:
| Gepubliceerd in: | Bioorg Med Chem Lett |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6129981/ https://ncbi.nlm.nih.gov/pubmed/30076049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.07.033 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|