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Effects of chidamide and its combination with decitabine on proliferation and apoptosis of leukemia cell lines

Chidamide, a novel histone deacetylase inhibitor (HDACI), shows anticancer ability against leukemia and solid tumors. Decitabine (5-Aza-2’-deoxycytidine, DAC), an anti-leukemic drug, is effective in treating acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). In our study, we investigat...

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Vydáno v:Am J Transl Res
Hlavní autoři: Mao, Jianping, Li, Shan, Zhao, Huihui, Zhu, Yu, Hong, Ming, Zhu, Han, Qian, Sixuan, Li, Jianyong
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129529/
https://ncbi.nlm.nih.gov/pubmed/30210693
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