Immunization with Mycobacterium vaccae induces an anti-inflammatory milieu in the CNS: attenuation of stress-induced microglial priming, alarmins and anxiety-like behavior

Exposure to stressors induces anxiety- and depressive-like behaviors, which are mediated, in part, by neuroinflammatory processes. Recent findings demonstrate that treatment with the immunoregulatory and anti-inflammatory bacterium, Mycobacterium vaccae (M. vaccae), attenuates stress-induced exagger...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Frank, Matthew G., Fonken, Laura K., Dolzani, Samuel D., Annis, Jessica L., Siebler, Philip H., Schmidt, Dominic, Watkins, Linda R., Maier, Steven F., Lowry, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129419/
https://ncbi.nlm.nih.gov/pubmed/29807129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2018.05.020
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